WS-12 Powder
Basic information WS-12 powder
- Product name:WS-12 powder
- Specification:99%
- MF:C18H27NO2
- Molecular weight:289.41859000
- CAS NO:68489-09-8
- Appearance:White powder
What is WS-12 powder?
Cooling Agent WS-12 powder is a potent TRPM8 agonist that acts as a cooling agent (EC50 = 193 nM). It robustly activated TRPM8 in low micromolar concentrations (EC50 12+/-5 microM) thereby displaying a higher potency and efficacy compared to menthol (EC50 196+/-22 microM). The selectivity profile of WS-12, its several-fold higher potency and around two-fold increase in efficacy compared to menthol warrants its potential utility for therapy in chronic neuropathic pain states and as a diagnostic probe in prostate cancer.
It is a menthol derivative. But unlike menthol, it is virtually nonvolatile, odorless and tasteless. It offers one of the strongest initial cooling impacts and a significantly longer lasting effect comparing with such conventional coolants such as WS-3, WS-5, and WS-23. It has potential for use in mint flavors in oral care applications as well as confectionary and chewing gum depending on dosage levels. In addition it can be used at low levels to impart freshness into berry, citrus and other fruit flavors in a variety of applications. WS-12 has been found to cool primarily at the front of the tongue.
Benefits of WS-12 powder
- Daily use products: Toothpaste, oral products, Air Freshener, skin cream, shaving cream, shampoo, sunscreen, shower cream.
- Food products: Confectionery products, chocolate, dairy produce, beer, distilled spirit, beverage,chewing Gum.
- Medicine: Linctus, diminish inflammation ointment, dyspepsia, antipruritic, liniment, oral cavityacesodyne, heatstroke pill.
- Others: Cigarette, filter tip and other tobacco, it also can be used for driving insects.
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Packing & Storage
Pack in paper-drums and two plastic-bags inside. Net Weight: 25kgs/paper-drum.
1kg-5kgs plastic bag inside with aluminum foil bag outside. Net Weight: 20kgs-25kgs/paper-drum.
Store in a well-closed container away from moisture and light.
Shelf life
2 years if sealed and store away from direct sun light.